Awareness Day
Mastocytosis & Mast Cell Diseases
The Awareness Day takes place annually on October 20.
Awareness Day 2021
The fourth Awareness Day took place on October 20, 2021.
You can find more information on mastocytosis-mcas.org.
The Awareness Day takes place annually on October 20.
07.10.2021
What are Mast Cells?
Mast Cell are a part of the immune system.They're found in the most issues troughout the body, especially those that interact with the outside world, including the lungs, gastrointestinal tract and skin.
When a Mast Cell is activated by a trigger it releases many mediators (chemicals that sett of processed that lead to symptoms). Histamine is one off 200> mediators which Mast Cells may release. histamin
Mast Cell Disease happens, when this cells aren't behaving normally, and reactions can be amplified in people who have to many Mast Cells.
When a Mast Cell is activated by a trigger it releases many mediators (chemicals that sett of processed that lead to symptoms). Histamine is one off 200> mediators which Mast Cells may release. histamin
Mast Cell Disease happens, when this cells aren't behaving normally, and reactions can be amplified in people who have to many Mast Cells.
08.10.2021
Fainting! Swelling! Nausea! Hives! GI Issues!
All of these are common symptoms of mastocytosis, a rare disease that affects hundreds of thousands of people globally
Those with Mastocytosis never know what their day will be like since their symptoms come about unexpectedly and swiftly.
Discover how Mastocytosis can impact people, and how you can help raise awareness.
Visit mastocytosis-mcas.org
Mastocytosis is a group of conditions in which people produce too many mast cells. The overproduction of mast cells can be limited to one part of the body (most commonly the skin) or the cells can be found in many body tissues such as the skin, GI tract, respiratory tract, bone marrow, spleen, and liver.
When the mast cells are in the skin we call that cutaneous mastocytosis, and those extra mast cells can cause skin lesions that vary widely in appearance.
When mast cells are in a range of body tissues we call that systemic mastocytosis. Systemic mastocytosis can be indolent (which means lazy) where the mast cells reproduce relatively slowly. In the less common more advanced forms, the mast cells reproduce more quickly and need strong medications that can decrease the mast cell burden.
Anyone with mastocytosis can experience symptoms in a range of body tissues because the chemical mediators released by the mast cells can travel around the body.
Those with Mastocytosis never know what their day will be like since their symptoms come about unexpectedly and swiftly.
Discover how Mastocytosis can impact people, and how you can help raise awareness.
Visit mastocytosis-mcas.org
Mastocytosis is a group of conditions in which people produce too many mast cells. The overproduction of mast cells can be limited to one part of the body (most commonly the skin) or the cells can be found in many body tissues such as the skin, GI tract, respiratory tract, bone marrow, spleen, and liver.
When the mast cells are in the skin we call that cutaneous mastocytosis, and those extra mast cells can cause skin lesions that vary widely in appearance.
When mast cells are in a range of body tissues we call that systemic mastocytosis. Systemic mastocytosis can be indolent (which means lazy) where the mast cells reproduce relatively slowly. In the less common more advanced forms, the mast cells reproduce more quickly and need strong medications that can decrease the mast cell burden.
Anyone with mastocytosis can experience symptoms in a range of body tissues because the chemical mediators released by the mast cells can travel around the body.
09.10.2021
Imaging being in a store and walking by someone wearing perfume. Suddenly your skin itches, you start wheezing, you feel pain-maybe even faint!
For some people with mast cell disease, this is a constant fear. This may be a symptom of Mast Cell Activation Syndrom (MCAS). Symptoms may flare, or increase as a result of the underlying cascade of release of mediators, which is kargely unpredictable, and can be excrutiating and debilitating.
Discover how MCAS can impact people, and how you can help rais awareness.
Visit mastocytosis-mcas.org
In mast cell activation syndromes, people have symptoms of mast cells being activated even though they have a normal number of mast cells. Their mast cells are being triggered inappropriately. Chemical mediators released by those mast cells can cause symptoms such as flushing, itching, hives, headache, gastrointestinal symptoms and low blood pressure.
Discover how MCAS can impact people, and how you can help rais awareness.
Visit mastocytosis-mcas.org
In mast cell activation syndromes, people have symptoms of mast cells being activated even though they have a normal number of mast cells. Their mast cells are being triggered inappropriately. Chemical mediators released by those mast cells can cause symptoms such as flushing, itching, hives, headache, gastrointestinal symptoms and low blood pressure.
10.10.2021
Symptoms may vary considerably and can be unbearable or so mild they are not even noticed.
This new identified condition can cause anaphylaxis, Gi pain, joint pain and make the plood pressure unstable.
Discover how HaT can impact people and how you can help raise awarness.
Visit mastocytosis-mcas.org
Tryptase is one of many chemicals produced by mast cells. Researchers have recently identified people who make extra copies of the alpha tryptase gene. This is called Hereditary Alpha Tryptasemia (HaT). This genetic trait leads to increased levels of tryptase in the blood. Having extra copies of this gene may or may not cause symptoms
Some people with this genetic trait have symptoms similar to those in mastocytosis and MCAS, in particular, food intolerances with abdominal pain and diarrhea, as well as flushing and swelling of the skin and generalized aches and pains and dizzy spells. Some people with HaT are prone to anaphylaxis. This condition can usually be excluded if the tryptase level is less than 8 ng/ml. Because this condition is so recently identified there is still a lot to learn about what symptoms might be associated with it and how best to treat it.
People can have mastocytosis and HaT, both, or just have one.
Discover how HaT can impact people and how you can help raise awarness.
Visit mastocytosis-mcas.org
Tryptase is one of many chemicals produced by mast cells. Researchers have recently identified people who make extra copies of the alpha tryptase gene. This is called Hereditary Alpha Tryptasemia (HaT). This genetic trait leads to increased levels of tryptase in the blood. Having extra copies of this gene may or may not cause symptoms
Some people with this genetic trait have symptoms similar to those in mastocytosis and MCAS, in particular, food intolerances with abdominal pain and diarrhea, as well as flushing and swelling of the skin and generalized aches and pains and dizzy spells. Some people with HaT are prone to anaphylaxis. This condition can usually be excluded if the tryptase level is less than 8 ng/ml. Because this condition is so recently identified there is still a lot to learn about what symptoms might be associated with it and how best to treat it.
People can have mastocytosis and HaT, both, or just have one.
11.10.2021
Can children have a mast cell disease?
A rare disease causes children to have blisters on their skin, feel itchy, achy, fatigued, and/or confused.
Mastocytosis and mast cell diseases impact adults with similar symptoms, but when it happens in children it seems particulary challenging.
Discover how mastocytosis and mast cell diseases can impact people, and how you can help raise awareness.
Visit mastocytosis-mcas.org
Did you know that children can also have mast cell disease?
Mastocytosis and mast cell diseases impact adults with similar symptoms, but when it happens in children it seems particulary challenging.
Discover how mastocytosis and mast cell diseases can impact people, and how you can help raise awareness.
Visit mastocytosis-mcas.org
Did you know that children can also have mast cell disease?
12.10.2021
Have you ever gotten a bad skin rash?
Discover how mastocytosis and mast cell diseases can impact people, and how you can help raise awareness.
Visit mastocytosis-mcas.org
Have you ever gotten a bad skin rush?
Imagine experiencing a hot, potientally itchy rash, unexpectedly and suddenly, at any time. It could affect just one area of your body or your entire body. Inside and out. It could last for one hour or forever!
That is what it can be like to live live with mastocytosis and mast cell diseases.
Visit mastocytosis-mcas.org
Have you ever gotten a bad skin rush?
Imagine experiencing a hot, potientally itchy rash, unexpectedly and suddenly, at any time. It could affect just one area of your body or your entire body. Inside and out. It could last for one hour or forever!
That is what it can be like to live live with mastocytosis and mast cell diseases.
14.10.2021
You go to your favorite restaurant and order your favorite meal. Before you can finish it you find you are flushed, itchy, short of breath, close to fainting.
For some peoples with mast cell diseases, the slightest change in a food-a new spice, a new supplier for an ingredient-can trigger a radical "flare".
Learn more about what people with mast cell diseases must do to keep themselves save.
Discover how mast cell diseases can impact people, and how you can help raise awareness.
Visit mastocytosis-mcas.org
Learn more about what people with mast cell diseases must do to keep themselves save.
Discover how mast cell diseases can impact people, and how you can help raise awareness.
Visit mastocytosis-mcas.org
15.10.2021
Your thoughts are cloudy, murky. You can't seem to remember simple things-a string of numbers, where you put your keys, what you did last week.
They call it brain fog
We all have have it from tim to time, when we are exhausted, stressed dealing with trauma. But brain fog is a daily experience for people with mastocytosis and mast cell diseases. What are these diseases?
Discover how mastocytosis and mast cell diseases can impact people, and how you can help raise awareness.
Visit mastocytosis-mcas.org
We all have have it from tim to time, when we are exhausted, stressed dealing with trauma. But brain fog is a daily experience for people with mastocytosis and mast cell diseases. What are these diseases?
Discover how mastocytosis and mast cell diseases can impact people, and how you can help raise awareness.
Visit mastocytosis-mcas.org
16.10.2021
Living with a rare disease
Living with a mast cell disease can feel like living in a minefield, because so many "normal" things, like foods or washing powder or a hot day can cause misery.
Staying safe by advoiding these triggers can make some people with mast cell diseases feel quite isolated.
It can be difficult to diagnose these conditions because they are rare (so doctors may not have seen patients with them before).
Discover how mast cell diseases can impact people, and how you can help raise awareness.
Visit mastocytosis-mcas.org
Staying safe by advoiding these triggers can make some people with mast cell diseases feel quite isolated.
It can be difficult to diagnose these conditions because they are rare (so doctors may not have seen patients with them before).
Discover how mast cell diseases can impact people, and how you can help raise awareness.
Visit mastocytosis-mcas.org
17.10.2021
Find your local support organisation
Our Global Support Directory offer patients from different countries a common plattform to seek information about mastocytosis and mast cell diseases.
We link you to various patient support websites from around the globe to facilitate human networking and enable you to seek local support.
Visit mastocytosis-
mcas.org/global-support/
We link you to various patient support websites from around the globe to facilitate human networking and enable you to seek local support.
Visit mastocytosis-
mcas.org/global-support/
