HαT

Hereditary Alpha Tryptasemia (HαT) is a common genetic trait found in about 5% of the studied populations.

It’s caused by having extra copies of a gene called TPSAB1, which makes a protein called α-tryptase. HαT can lead to various symptoms.

Up to two-thirds of patients with HαT do not experience any significant symptoms. However, in certain situations it may increase the risk of severe allergic reactions such as anaphylaxis.